
The functional medicine club for people who are done being told they’re “fine.”
Physician-led care, in-depth lab testing and one team of practitioners who actually talk to each other.
Saffron & Sage is a members-based integrative clinic on State Street, just north of Little Italy. We look at your whole picture, find what’s driving how you feel, and build a plan with you. Then we keep checking the data as you go.
- Physician-led, with a medical director
- 3 to 5 practitioners on your team
- Lab-driven plans
- HSA, FSA and LSA welcome
You’ve done the appointments. You still don’t have answers.
Most people who find us aren’t looking for a treat. They’re looking for someone to finally connect the dots.

Your labs are “normal.” You aren’t.
You’ve been told everything looks fine, but you still don’t feel like yourself. Standard ranges don’t always tell the full story.
See how we test
Energy that crashes by 3 PM
Coffee, sugar, a second wind that never comes. You want steady energy, not another workaround.
The 3 PM problem
Brain fog you can’t shake
Slower recall, less focus, more effort for the same output. For people who think for a living, that’s expensive.
Mental bandwidth
A diagnosis, and a lot of open questions
Thyroid, autoimmune, gut or a chronic condition you’re managing. You want a team that looks at all of it together.
Autoimmunity, explained
Specialists who never talk to each other
Five providers, five opinions, no plan. Here, your practitioners meet about you and work from one plan.

You want to stay sharp for decades
You’re not sick. You just want the data and a plan to keep performing at 60 the way you do at 40.
Longevity biomarkersNot a spa. Not a seven-minute visit. A care team that knows your whole story.
Functional medicine asks why. Why you’re tired, why your gut is off, why your labs don’t match how you feel. Then it builds a plan around the answer.
At Saffron & Sage, that work is done by a team: a medical director, naturopathic doctors, doctors of acupuncture and Chinese medicine, nurses, therapists and movement practitioners. Most members work with three to five of them. They share your history, your labs and your goals, so you never have to start from zero.
We don’t promise cures, and we don’t sell packages you don’t need. We measure where you are, agree on what matters most to you, and adjust as your data changes.
The Saffron Method
Our collaborative care model: test to see the full picture, plan with a team, support with care that fits your life, and re-test to see what’s working. Meet the collaborative care team

From first call to a plan you can see working
Membership is how we stay with you after the first visit. Instead of one-off appointments, you get a team, a plan and a monthly rhythm of care.
- A free discovery call. A short call with our team. Tell us what’s going on and what you want. We’ll tell you honestly whether we’re the right fit.
- Your first visit and consultation. A practitioner goes through your history, symptoms, medications and goals in depth. $300 for new members, normally $600.
- Testing that shows the full picture. Labs and, for many members, the Integrative Physical: a two-hour, head-to-toe assessment with our medical team.
- Your care team and your plan. Three to five practitioners, one shared plan, built around your priorities and your calendar.
- Membership that keeps it moving. Monthly credits for care, regular check-ins and re-testing, so the plan adapts as your results change.
Inside Saffron & Sage
A bright, quiet clinic on State Street, built for care that takes its time.



Clear pricing. Two ways to start.
Your first visit is where it starts. After that, membership gives you monthly credits for care, with your team and your plan in one place.
First visit and consultation
Your first appointment and a full consultation together.
Book your first visitNew members. Through October 31, 2026.
Your first appointment
Start with a single appointment, then decide what comes next.
Book my first appointmentNew members. Through October 31, 2026.
Then, as a member
Monthly credits for care across the clinic, your care team and regular check-ins. Ask us about membership on your discovery call.
Use pre-tax dollars
Welcome for many services. We’re direct pay and don’t bill insurance. How HSA, FSA and LSA work here
Your plan starts with your numbers, not a guess
Standard checkups test a handful of markers. We go further, so your plan is built on what’s actually happening in your body.
- Comprehensive blood panelsMetabolic, inflammation, nutrients
- Hormones and thyroidIncluding full thyroid panels
- Gut healthDigestion, microbiome
- Heart and metabolic healthCardiovascular assessment
- Fitness and performanceVO2 max testing
- GeneticsGenetic testing
Already have recent bloodwork? Upload it for a free educational overview →
Have your most recent labs? Upload them here for a free overview.
Upload a recent lab report and get a plain-language overview of what each marker measures. You arrive at your first visit with better questions, and our team starts from what you already have.
Upload my lab reportFree. Takes about a minute. Your file is processed in real time and is not stored. Educational only, not medical advice or a diagnosis.
- UploadA recent lab report, as a PDF or a photo.
- ReadA plain-language overview of what each marker measures.
- Talk it throughWith our team on a free discovery call, if you would like.
One clinic. Every piece of the plan.
Your care team pulls from everything under one roof, so your plan isn’t limited by what one practitioner happens to offer.

Medical & diagnostic
Precision care, overseen by our medical team.
Body & recovery
Hands-on care for pain, tension and recovery.

Mind & nervous system
Support for stress, sleep and focus.

Complex conditions
A team for the hard cases.
Meet the team behind your plan
Doctors and practitioners who work together on your case, not in separate silos.

Dr. John Kasawa
Medical oversight for clinical care at Saffron & Sage.

Dr. Kolin Durrant
Director of Clinical Operations. Functional medicine and Chinese medicine. Thyroid, autoimmune, digestive and skin.

Dr. Alexander Aponte-Davila
Naturopathic doctor and nutritionist. Labs, gut and hormones.

Dr. Nazanin Ghetmiri
Naturopathic doctor. Gut, endocrine and women’s health.

Dr. Scott McFarlane
Director of Clinical Excellence. Acupuncture, bodywork and the nervous system.

Dr. Mahshid
Holistic primary care. Sleep, stress and acupuncture.
Built for people who take their health as seriously as their work
Founders and executives
You run on your brain and your energy. We help you protect both, with data.
People with complex or chronic conditions
When one specialist at a time hasn’t worked, a team that looks at everything can.
Anyone done guessing
You want real answers and a clear plan, not another supplement from the internet.
Companies
Wellness events, memberships and executive health for teams. Corporate wellness →
Questions, answered
What is functional medicine?
An approach that looks for the root causes behind symptoms, using a detailed history, lab testing and a plan built around the whole person. At Saffron & Sage it’s delivered by a physician-led team that works alongside your other doctors.
Is Saffron & Sage a membership?
Yes. Members get monthly credits for care, a care team and ongoing check-ins. You can start with a first visit or a free discovery call before deciding on membership.
How much does it cost?
New members can book a first visit and consultation for $300, normally $600, or a first appointment for $250, normally $300, through October 31, 2026.
Do you take insurance?
We’re a direct pay clinic and don’t bill insurance. HSA, FSA and LSA dollars are welcome for many services. Check eligibility with your plan administrator.
Do I have to stop seeing my regular doctor?
No. We work alongside your primary care doctor and specialists, and we’re happy to coordinate with them.
What happens on the discovery call?
A short conversation with our team about what’s going on and what you want. There’s no cost and no pressure. If we’re not the right fit, we’ll tell you.
What is the Integrative Physical?
A two-hour, in-depth assessment with our medical team that many members start with. It gives your care team a full baseline to build your plan from.
Where are you, and when are you open?
2555 State St, Suite 101, San Diego, CA 92101, just north of Little Italy. Monday and Thursday 8 to 2, Tuesday, Wednesday and Friday 8 to 8.
Not ready to book? Start with a free guide.
Plain-language guides to the questions we hear most. Pick one, leave your email, and download it right away.
When the body won’t stand downFree · 12 pages
Normal for you is not the same as normalFree · 9 pages
When the thyroid panel says fineFree · 11 pages
When the room won’t hold stillFree · 12 pages
Reading your skinFree · 11 pages
Puffiness that isn’t weightFree · 9 pages
The waiting periodFree · 10 pages
Money you already set asideFree · 11 pagesStop guessing. Start with one conversation.
Tell us what’s going on. We’ll listen, answer your questions and tell you honestly whether membership is right for you. Free, and no pressure.
2555 State St, Suite 101, San Diego · Just north of Little Italy
Saffron & Sage provides integrative and functional medicine care alongside, not instead of, your primary care and specialist doctors. We don’t promise specific results; individual experiences vary. All medical services are provided by Kasawa Medical APC dba Saffron & Sage MD. In an emergency, call 911.

Not sure where to start?
Book a free discovery call. Tell us what’s going on, and we’ll tell you how we can help. First visits & consultation (2 hour session) are $300, normally $600, through October 31.
Request a free discovery callFree. No pressure. Or call (619) 933-2340.