The Link Between IUDs and Breast Cancer Risk: What You Need to Know
Author: Dr. Kolin Durrant, Integrative Care Director, Doctor of Acupuncture & Chinese Medicine
In recent years, new research has drawn attention to the possible relationship between hormonal intrauterine devices (IUDs) and an increased risk of breast cancer. While hormonal contraception remains a popular and effective option, it is important to understand how synthetic hormones may impact long-term health.
At Saffron and Sage, we guide women through these complex decisions by combining scientific evidence with integrative care planning. Our goal is to support each individual in making informed, empowered choices aligned with their overall wellbeing.
Understanding Hormonal IUDs
Hormonal IUDs such as Mirena, Kyleena, Liletta, and Skyla release levonorgestrel, a synthetic form of progesterone, directly into the uterus. These devices are highly effective for contraception and often reduce menstrual bleeding and cramping. However, levonorgestrel can enter the bloodstream, influencing other hormone-sensitive tissues throughout the body, including the breasts.
Although hormonal IUDs primarily act locally by thickening cervical mucus and thinning the uterine lining, systemic absorption has been documented. This raises valid questions about potential effects beyond reproductive function.
Reviewing the Evidence: IUDs and Breast Cancer
A 2024 Danish cohort study published in Acta Obstetricia et Gynecologica Scandinavica examined health records from over 78,000 women between the ages of 15 and 49 who used levonorgestrel-based IUDs. The researchers identified a 40 percent relative increase in breast cancer diagnoses compared to women with similar health profiles who did not use hormonal IUDs.
To contextualize this finding:
The average breast cancer risk for a woman in her 30s is about 1 in 204
A 40 percent increase adjusts this to approximately 1.4 in 204
This absolute risk remains relatively small, but the study aligns with similar findings from research on oral contraceptives and reinforces the importance of individualized risk assessment.
How Hormones Influence Breast Tissue
The connection between hormonal contraceptives and breast cancer risk lies in the biology of hormone-sensitive tissues. Estrogen and synthetic progestins like levonorgestrel can stimulate breast cell growth. Over time, increased cellular activity raises the potential for DNA mutations that may contribute to cancer development.
This does not imply that hormonal contraceptives cause cancer. Rather, they may increase the susceptibility in women with predisposing genetic, lifestyle, or hormonal risk factors (Breastcancer.org, 2023).
Risk Factors to Consider
Before initiating or continuing hormonal contraception, it is important to evaluate the following variables:
Genetic predisposition such as BRCA1 or BRCA2 mutations or a strong family history of breast cancer
Hormonal sensitivity, especially for women who have experienced side effects from other forms of synthetic hormone exposure
Lifestyle factors including poor dietary patterns, alcohol consumption, lack of physical activity, and chronic stress
Duration of hormonal exposure, as longer-term use may influence cumulative risk over time
These considerations help determine whether a hormonal IUD is appropriate or whether alternative options may better support your health goals.
Holistic Health Approaches to Contraception
For women seeking hormone-free options, a number of holistic and evidence-informed alternatives exist:
Fertility awareness methods involve tracking ovulation using basal body temperature and cervical mucus changes. When practiced correctly, these methods can be both safe and effective.
Copper IUDs provide long-term contraception without hormone release and may be preferable for women with estrogen or progesterone sensitivity.
Herbal support using botanicals such as chasteberry (Vitex agnus-castus) can assist in regulating the menstrual cycle and supporting endogenous progesterone production.
Lifestyle-based hormone regulation through diet, exercise, acupuncture, breathwork, and stress reduction can help maintain hormonal balance naturally.
These options can be customized in collaboration with an integrative provider to suit your specific needs and comfort level.
The Importance of Continued Research
Although recent studies raise important questions, more longitudinal data is needed to clarify the relationship between IUD use and breast cancer risk. Future research should investigate dosage effects, duration of exposure, and interactions with individual risk factors including genetics and lifestyle.
As integrative providers, we do not rely solely on a single study or protocol. We combine clinical research, patient history, and holistic frameworks to help each individual make decisions that feel aligned and informed.
Informed Choices Begin with You
Choosing a method of contraception is not just a medical decision. It impacts your physiology, emotional wellbeing, and overall sense of autonomy. There is no one-size-fits-all solution. Instead, there is a path that respects your body’s wisdom, your life circumstances, and your vision for the future.
If you are using or considering a hormonal IUD, we encourage open discussion with a trusted integrative provider who can assess your health history and guide you through all available options, including both conventional and holistic strategies.
Explore Holistic Contraception Support at Saffron and Sage
At Saffron and Sage, we offer comprehensive consultations for hormonal health, fertility awareness, and integrative birth control planning. Our providers work collaboratively to assess your risk factors, review lab data, and offer solutions that are rooted in both science and self-awareness.
Whether you are seeking to transition off hormonal contraceptives, manage side effects, or explore natural fertility methods, we are here to support your journey.
Call 619-933-2340 or schedule your consultation today to explore holistic alternatives and discover how integrative care can support your long-term wellness.